Utility of cerebrovascular imaging biomarkers to detect cerebral amyloidosis.

Matthew D HoweMegan R CarusoMasood ManoochehriZachary J KunickiSheina EmraniJames L RudolphEdward D HueyStephen P SallowayHwamee Ohnull null

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)

Cerebrovascular biomarkers linked to amyloid beta (Aβ) in Alzheimer's disease (AD). White matter hyperintensities and cerebral microbleeds reliably predict Aβ-PET positivity. Relationships with Aβ-PET vary by cognitive stage. Novel accessible model predicts Aβ-PET status. Study supports multimodal diagnostic approaches.

Keyphrases

pet ct
positron emission tomography
white matter
computed tomography
subarachnoid hemorrhage
pet imaging
high resolution
cerebral ischemia
pain management
mass spectrometry
brain injury
chronic pain
mild cognitive impairment
fluorescence imaging