Crosstalk between diacylglycerol kinase and protein kinase A in the regulation of airway smooth muscle cell proliferation.

Miguel A Hernandez-LaraSantosh Kumar YadavStanley ConawaySushrut D ShahRaymond B PennDeepak A Deshpande

Published in: Respiratory research (2023)

-PKA) regulated by DGK in ASM cells and identifies DGK as a potential therapeutic target for mitigating ASM cell proliferation that contributes to airway remodeling in asthma.

Keyphrases

cell proliferation
smooth muscle
protein kinase
induced apoptosis
cell cycle arrest
cell cycle
pi k akt
chronic obstructive pulmonary disease
genome wide
endoplasmic reticulum stress
gene expression
cell death
human health
dna methylation