Heart rate variability and microvolt T wave alternans changes during ajmaline test may predict prognosis in Brugada syndrome.

Paul-Adrian CălbureanLuigi PannoneAntonio SorgenteAnaïs GautheyCinzia MonacoAntanas StrazdasAlexandre AlmoradAntonio BisignaniGezim BalaRobbert RamakIngrid OvereinderErwin StrökerGudrun PappaertSonia Van DoorenThomy de RavelMark La MeirPedro BrugadaJuan SieiraGian-Battista ChierchiaCarlo De Asmundis

Published in: Clinical autonomic research : official journal of the Clinical Autonomic Research Society (2023)

Ajmaline induced important HRV changes similar to those observed during isoproterenol. Increased mTWA was observed only in patients with BrS. BrS with VAs during follow-up presented worse changes during ajmaline test, including lower LF power and higher maximum mTWA which were independent predictors of events.

Keyphrases

heart rate variability
heart rate
high glucose
diabetic rats
case report
drug induced
oxidative stress
endothelial cells
stress induced