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Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial.

Sabrina PaganoniSuzanne HendrixSamuel P DicksonNewman KnowltonJames D BerryMichael A ElliottSamuel MaiserChafic KaramJames B CaressMargaret Ayo OwegiAdam QuickJames WymerStephen A GoutmanDaragh HeitzmanTerry D Heiman-PattersonCarlayne JacksonColin QuinnJeffrey D RothsteinEdward J KasarskisJonathan KatzLiberty JenkinsShafeeq S LadhaTimothy M MillerStephen N ScelsaTuan H VuChristina FournierKristin M JohnsonAndrea SwensonNamita GoyalGary L PatteeSuma BabuMarianne ChaseDerek DagostinoMeghan HallGale KittleMathew EydinovJoseph OstrowLindsay PothierRebecca RandallJeremy M ShefnerAlexander V ShermanEric TustisonPrasha VigneswaranHong YuJoshua CohenJustin KleeRudolph TanziWalter GilbertPatrick YeramianMerit Cudkowicz
Published in: Journal of neurology, neurosurgery, and psychiatry (2022)
NCT03127514; NCT03488524.
Keyphrases
  • free survival
  • mechanical ventilation
  • phase iii
  • study protocol
  • clinical trial
  • respiratory failure
  • phase ii
  • acute respiratory distress syndrome
  • intensive care unit
  • extracorporeal membrane oxygenation