The steroid hormone estriol (E 3 ) regulates epigenetic programming of fetal mouse brain and reproductive tract.
Yuping ZhouBaoxia GuGeraldine BrichantJay Prakash SinghHuan YangHao ChangYanding ZhaoChao ChengZhong-Wu LiuMyles H AldermanLingeng LuXiaoyong YangXiao-Bing GaoHugh S TaylorPublished in: BMC biology (2022)
in fetal reproductive system and brain. We further identify a novel mechanism of estrogen action, through recruitment of epigenetic modifiers to estrogen receptors and their target genes, which is not correlated with the traditional view of estrogen potency.