Neuroinflammation is induced by tongue-instilled ZnO nanoparticles via the Ca2+-dependent NF-κB and MAPK pathways.
Huimin LiangAijie ChenXuan LaiJia LiuJunrong WuYiyuan KangXinying WangLong-Quan ShaoPublished in: Particle and fibre toxicology (2018)
This study provided a new way how NPs, such as ZnO NPs, induce neuroinflammation via the taste nerve translocation pathway, a new mechanism for ZnO NPs-induced neuroinflammation and a new direction for nanomaterial toxicity analysis.
Keyphrases
- lps induced
- room temperature
- lipopolysaccharide induced
- quantum dots
- oxide nanoparticles
- traumatic brain injury
- oxidative stress
- signaling pathway
- inflammatory response
- cognitive impairment
- reduced graphene oxide
- cerebral ischemia
- visible light
- diabetic rats
- pi k akt
- high glucose
- light emitting
- gold nanoparticles
- toll like receptor
- endothelial cells
- ionic liquid
- data analysis