Long Noncoding RNAs in Yeast Cells and Differentiated Subpopulations of Yeast Colonies and Biofilms.
Derek WilkinsonLibuše VáchováOtakar HlaváčekJana MaršíkováGregor D GilfillanZdena PalkováPublished in: Oxidative medicine and cellular longevity (2018)
We summarize current knowledge regarding regulatory functions of long noncoding RNAs (lncRNAs) in yeast, with emphasis on lncRNAs identified recently in yeast colonies and biofilms. Potential regulatory functions of these lncRNAs in differentiated cells of domesticated colonies adapted to plentiful conditions versus yeast colony biofilms are discussed. We show that specific cell types differ in their complements of lncRNA, that this complement changes over time in differentiating upper cells, and that these lncRNAs target diverse functional categories of genes in different cell subpopulations and specific colony types.
Keyphrases
- induced apoptosis
- cell cycle arrest
- saccharomyces cerevisiae
- candida albicans
- single cell
- endoplasmic reticulum stress
- transcription factor
- genome wide analysis
- genome wide identification
- cell death
- stem cells
- cell wall
- oxidative stress
- magnetic resonance imaging
- cell therapy
- signaling pathway
- genome wide
- mesenchymal stem cells
- bone marrow