Validation of an automated immune turbidimetric assay for serum gelsolin and its possible clinical utility in sepsis.

Zoltán Horváth-SzalaiPéter KustánBalázs SzirmayÁgnes LakatosPer H ChristensenTamás HuberBeáta BugyiDiána MühlAndrea LudányAttila MisetaGábor L KovácsTamás Kőszegi

Published in: Journal of clinical laboratory analysis (2017)

Based on the results, our immune turbidimetric measurement offers a rapid and accurate quantitation of gelsolin in human serum samples. Serum gelsolin seems a promising additional diagnostic marker of sepsis which has to be further investigated.

Keyphrases

septic shock
acute kidney injury
intensive care unit
ms ms
mass spectrometry
high resolution
liquid chromatography
high performance liquid chromatography
tandem mass spectrometry
loop mediated isothermal amplification
solid phase extraction
single molecule