NT157 Inhibits HCC Migration via Downregulating the STAT3/Jab1 Signaling Pathway.

SiZhe YuYu WangKeJia LvJia HouWenYuan LiXiao WangHui GuoWenJuan Wang

Published in: Technology in cancer research & treatment (2022)

NT157 inhibits hepatocellular carcinoma migration and metastasis by downregulating the signal transducer and activator of transcription-3/c-Jun activation domain-binding protein-1 signaling pathway and targeting it may serve as a novel therapeutic strategy for the clinical management of hepatocellular carcinoma in the future.

Keyphrases

signaling pathway
binding protein
pi k akt
epithelial mesenchymal transition
induced apoptosis
cell proliferation
transcription factor
cancer therapy
current status
nuclear factor
oxidative stress
drug delivery