Involvement of collagen XVII in pluripotency gene expression and metabolic reprogramming of lung cancer stem cells.

Han-Shui HsuChen-Chi LiuJiun-Han LinTien-Wei HsuJyuan-Wei HsuAnna Fen-Yau LiShih-Chieh Hung

Published in: Journal of biomedical science (2020)

These data suggest the Oct4-HK2 pathway regulated by collagen XVII plays an important role in metabolic reprogramming and maintenance of CSC-like features in lung CSCs, which may aid in the development of new strategies in cancer treatment.

Keyphrases

cancer stem cells
gene expression
dna methylation
wound healing
tissue engineering
electronic health record
optical coherence tomography
big data
diabetic retinopathy
high glucose
endothelial cells
embryonic stem cells
data analysis