Higher Estradiol and Lower Dehydroepiandrosterone-Sulfate Levels Are Associated with Pulmonary Arterial Hypertension in Men.
Corey E VentetuoloGrayson L BairdR Graham BarrDavid A BluemkeJason S FritzNicholas S HillJames R KlingerJoao A C LimaPamela OuyangHarold I PalevskyAmy J PalmiscianoIpsita KrishnanDiane PinderIoana R PrestonKari E RobertsSteven M KawutPublished in: American journal of respiratory and critical care medicine (2017)
Higher levels of E2 and lower levels of DHEA-S were associated with PAH in men. Sex-based differences in sex hormone processing and signaling may contribute to unique phenotypes in pulmonary vascular disease.