Mitochondrial bioenergetics boost macrophages activation promoting liver regeneration in metabolically compromised animals.
Naroa Goikoetxea-UsandizagaMarina Serrano-MaciáTeresa C DelgadoJorge SimónDavid Fernández RamosDiego BarrialesMaria E CornideMónica JiménezMarina Pérez-RedondoSofia Lachiondo-OrtegaRubén Rodríguez-AgudoMaider BizkarguenagaJuan Diego ZalameaSamuel T PascoDaniel Caballero-DíazBenedetta AlfanoMiren BravoIrene González-RecioMaría Luz Martinez-ChantarClàudia Gil-PitarchJon MabeJordi Gracia-SanchoLeticia AbeciaÓscar LorenzoPaloma Martín-SanzNicola G A AbresciaGuadalupe SabioMercedes RincónJuan AnguitaEduardo Miñambres GarcíaCésar MartínMarina BerenguerIsabel FabregatMarta CasadoCarmen Peralta UrozMarta Varela-ReyMaría Luz Martínez-ChantarPublished in: Hepatology (Baltimore, Md.) (2021)
Boosting mitochondrial activity by silencing MCJ could pave the way for a novel protective approach after major liver resection or IRI, specially in metabolically compromised, IRI susceptible organs.
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