Monitoring Circulating Immune Checkpoint Proteins as Predictors of Non-AIDS Morbid Events in People With HIV Initiating Antiretroviral Therapy.
Thomas A PremeauxCarlee B MoserAshley McKhannMartin HoeniglStephen T YeungAlina P S PangMichael J CorleyMichael M LedermanAlan L LandaySara GianellaLishomwa C NdhlovuPublished in: Open forum infectious diseases (2022)
While select soluble ICPs were associated with non-AIDS events, CD27 emerged as a consistent marker irrespective of ART. Our data may offer guidance on new targets for early clinical monitoring in people with HIV who remain at greater risk of specific non-AIDS events.