One-step synthesis of green emission carbon dots for selective and sensitive detection of nitrite ions and cellular imaging application.
Minghui ZanCong LiFei LiaoLang RaoQian-Fang MengWei XieBei ChenXingwang QieLi LiLiang WangWen-Fei DongWei LiuPublished in: RSC advances (2020)
In recent years, carbon dot (CD)-based fluorescent sensors for selective ions or small biomolecules have drawn great attention. In this work, highly fluorescent CDs (QY = 21%) were prepared from 2,3-diamino pyridine as the precursor through a facile solvothermal process. The CDs showed high stability and a green emission in aqueous, and the optimal emission wavelength of CDs is 508 nm under the excitation wavelength of 438 nm. Interestingly, a CDs-based nanoprobe was developed for a selective and sensitive fluorescence quenching response to NO 2 - in water, and the quenching mechanism was investigated in the work. Besides, the recovery rates of NO 2 - in the range of 98-103.5% were found to be acceptable, indicating that the proposed CDs could be act as potential candidates for determination of nitrite ions in real samples. Meanwhile, the nanoprobe was also successfully employed in a visualization biosensing platform for determination of NO 2 - in living cells due to its eminent biocompatibility.
Keyphrases
- quantum dots
- energy transfer
- sensitive detection
- living cells
- fluorescent probe
- single molecule
- nitric oxide
- photodynamic therapy
- high resolution
- high throughput
- solid phase extraction
- molecularly imprinted
- loop mediated isothermal amplification
- solid state
- ionic liquid
- atomic force microscopy
- mass spectrometry
- gold nanoparticles
- human health
- metal organic framework
- high speed
- electron microscopy