Rheumatoid Arthritis as a Risk Factor for Coronary Artery Calcification and Obstructive Coronary Artery Disease in Patients with Chest Pain: A Registry Based Cross-Sectional Study.
Andreas Bugge TinggaardAnnette de ThurahIna Trolle AndersenAnders Hammerich RiisJosephine TherkildsenSimon WintherEllen Margrethe HaugeNiels Ramsing HolmPublished in: Clinical epidemiology (2020)
This is the first large-scale, CTA-based study examining the occurrence and severity of CAD in RA patients with symptoms suggestive of cardiovascular disease. A higher prevalence of coronary artery calcification was found in RA patients. After adjusting for age, sex, cardiovascular risk factors and comorbidities, the tendency was less pronounced. We found a trend for increased coronary calcification in RA patients being seropositive or needing treatment with GCI for a relapse or flare.
Keyphrases
- coronary artery
- rheumatoid arthritis
- coronary artery disease
- end stage renal disease
- chronic kidney disease
- cardiovascular risk factors
- cardiovascular disease
- ejection fraction
- pulmonary artery
- prognostic factors
- ankylosing spondylitis
- heart failure
- percutaneous coronary intervention
- peritoneal dialysis
- metabolic syndrome
- risk assessment
- pulmonary arterial hypertension
- coronary artery bypass grafting
- atrial fibrillation
- physical activity
- depressive symptoms
- systemic lupus erythematosus
- pulmonary hypertension
- combination therapy
- left ventricular