A population pharmacokinetic model to guide clozapine dose selection, based on age, sex, ethnicity, body weight and smoking status.

Suzanne J ReevesJulie BertrandStephen John ObeeSamora HunterRobert HowardRobert James Flanagan

Published in: British journal of clinical pharmacology (2023)

. The analysis was however limited by the absence of data on clinical outcome and future studies are required to determine optimal pre dose concentrations specifically in those aged over 65 years.

Keyphrases

body weight
electronic health record
smoking cessation
current status
big data
machine learning
case control
data analysis
artificial intelligence