Randomised clinical trial: effects of MD-7246 on irritable bowel syndrome with diarrhoea.

Anthony J LemboBraden KuoRamesh BoinpallyElla LiMadhuja MallickWieslaw BochenekWilmin Bartolini

Published in: Alimentary pharmacology & therapeutics (2022)

MD-7246 at the doses studied did not improve abdominal pain relative to placebo in an IBS-D patient population. Similarly, most additional efficacy endpoints showed no improvement with MD-7246 relative to placebo.

Keyphrases

irritable bowel syndrome
double blind
clinical trial
abdominal pain
molecular dynamics
phase iii
placebo controlled
open label
study protocol
phase ii
case report