Ginsenoside Rh2 mitigates doxorubicin-induced cardiotoxicity by inhibiting apoptotic and inflammatory damage and weakening pathological remodelling in breast cancer-bearing mice.
Jingang HouYeejin YunChanghao CuiSunchang KimPublished in: Cell proliferation (2022)
Rh2 regulates multiple pathways in the Dox-provoked heart, proposing a potential candidate for cancer supplement and therapy-associated cardiotoxicity.
Keyphrases
- oxidative stress
- papillary thyroid
- diabetic rats
- cell death
- high glucose
- heart failure
- squamous cell
- drug delivery
- signaling pathway
- high fat diet induced
- childhood cancer
- drug induced
- cancer therapy
- anti inflammatory
- squamous cell carcinoma
- radiation therapy
- radiation induced
- endothelial cells
- bone marrow
- insulin resistance
- mesenchymal stem cells
- metabolic syndrome
- climate change
- cell therapy