Genetic Links Between Metabolic Syndrome and Osteoarthritis: Insights from Cross-Trait Analysis.

Ji-Xiang HuangShu-Zhen XuTian TianJing WangLing-Qiong JiangTian HeShi-Yin MengJing NiHai-Feng Pan

Published in: The Journal of clinical endocrinology and metabolism (2024)

Our results illustrate a common genetic architecture, pleiotropic loci, as well as causality between MetS and OA, potentially enhancing our knowledge of high comorbidity and genetic processes that overlap between the two disorders.

Keyphrases

genome wide
metabolic syndrome
copy number
dna methylation
healthcare
knee osteoarthritis
rheumatoid arthritis
emergency department
type diabetes
adipose tissue
uric acid
skeletal muscle