A search to the target tissue in which RA-specific inflammation starts: a detailed MRI study to improve identification of RA-specific features in the phase of clinically suspect arthralgia.

Xanthe Marijn Edmée MatthijssenFenne WoutersDebbie M BoetersAleid C BoerYousra J DakkakEllis NiemantsverdrietAnnette H M van der Helm-van Mil

Published in: Arthritis research & therapy (2019)

Tenosynovitis, particularly MCP-extensor peritendinitis, is among the first tissues affected by RA. Incorporating this feature and number of locations with subclinical inflammation improved prediction making with PPVs up to 63-67%.

Keyphrases

rheumatoid arthritis
oxidative stress
disease activity
ankylosing spondylitis
gene expression
machine learning
contrast enhanced
deep learning
systemic lupus erythematosus
bioinformatics analysis
neural network