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Honokiol Suppresses Cell Proliferation and Tumor Migration through ROS in Human Anaplastic Thyroid Cancer Cells.

Kai-Sheng LiaoYing-Ray LeeWen-Ying ChaoYen-Ju HuangHui-Chen ChungShu-Hsin ChenYi-Zhen LiPei-Wen ZhaoHong-Yi Chang
Published in: Endocrine, metabolic & immune disorders drug targets (2024)
Taken together, we provided the potential mechanism for treating ATC cells with honokiol, which significantly suppresses tumor proliferation and inhibits tumor metastasis in vitro through reactive oxygen species (ROS) induction.
Keyphrases
  • reactive oxygen species
  • signaling pathway
  • cell proliferation
  • induced apoptosis
  • cell death
  • dna damage
  • endothelial cells
  • cell cycle arrest
  • oxidative stress
  • pi k akt
  • human health