A Negative Feedback Loop Between NAMPT and TGF-β Signaling Pathway in Colorectal Cancer Cells.

Xiaoqun LvJinguo ZhangJun ZhangWencai GuanWeifang RenYujuan LiuGuoxiong Xu

Published in: OncoTargets and therapy (2021)

There is a negative feedback loop between NAMPT and the TGF-β signaling pathway in CRC cells, providing new insight into the mechanism underlying the regulatory pathways in CRC.

Keyphrases

signaling pathway
induced apoptosis
pi k akt
transforming growth factor
transcription factor
cell cycle arrest
epithelial mesenchymal transition
endoplasmic reticulum stress
oxidative stress
cell proliferation
cell death