Login / Signup
Large-scale loss-of-function perturbations reveal a comprehensive epigenetic regulatory network in breast cancer.
Yumei Wang
Haiyan Wang
Wei Shao
Yuhui Chen
Yu Gui
Chao Hu
Xiaohong Yi
Lijun Huang
Shasha Li
Dong Wang
Published in:
Cancer biology & medicine (2023)
Our work deciphered the extensive regulation among hundreds of epigenetic regulators. The identification of 10 master epigenetic regulators offers promising therapeutic targets for breast cancer treatment.
Keyphrases
</>
dna methylation
gene expression
transcription factor
genome wide
single cell