Dynein at kinetochores: Making the connection.

Published in: The Journal of cell biology (2017)

Dynein removes the checkpoint proteins from kinetochores once chromosomes are bioriented. In this issue, Gama et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201610108) and Mosalaganti et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201611060) reveal the molecular basis for how dynein and its adaptor protein Spindly are recruited to the ROD-Zw10-Zwilch complex in the fibrous corona of unattached kinetochores.

Keyphrases

single cell
cell therapy
dna damage
mesenchymal stem cells
cell cycle
oxidative stress
protein protein