Cryptococcal Meningitis: A Retrospective Cohort of a Brazilian Reference Hospital in the Post-HAART Era of Universal Access.
Aline Z de AzambujaGustavo Wissmann NetoGuilherme WatteLuciana AntoniolliLuciano Z GoldaniPublished in: The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale (2018)
Meningeal cryptococcosis mostly caused by C. neoformans continues to occur predominantly in HIV-infected adults despite HAART being widely distributed in Brazil. Cryptococcosis remains a significant opportunistic infection in solid organ transplant recipients. Despite adequate antifungal treatment and management of intracranial hypertension in a reference tertiary care hospital, mortality was high. Identification of risk factors and additional treatment modalities, especially for intracranial hypertension, are necessary to improve care for patients with cryptococcal meningitis.
Keyphrases
- risk factors
- hiv infected
- blood pressure
- healthcare
- tertiary care
- palliative care
- type diabetes
- emergency department
- antiretroviral therapy
- cardiovascular disease
- cerebrospinal fluid
- hiv infected patients
- cardiovascular events
- combination therapy
- human immunodeficiency virus
- hepatitis c virus
- optic nerve
- pain management
- neural network