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Evaluating the Incidence of Opioid-Induced Respiratory Depression Associated with Oliceridine and Morphine as Measured by the Frequency and Average Cumulative Duration of Dosing Interruption in Patients Treated for Acute Postoperative Pain.

Sabry Salama AyadMark A DemitrackDavid A BurtCathy MichalskyLinda WaseMichael J FosslerAshish K Khanna
Published in: Clinical drug investigation (2020)
Using DI as a surrogate for OIRD indicates improved respiratory safety with oliceridine versus morphine that merits further investigation.
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