Distinct differences in gut microbial composition and functional potential from lean to morbidly obese subjects.

Abraham S MeijnikmanO AydinA ProdanV TremaroliH HerremaE LevinY AchermanS BruinV E GerdesF BackhedA K GroenM Nieuwdorp

Published in: Journal of internal medicine (2020)

Based on the faecal microbiota composition, we were able to separate subjects with and without obesity. In addition, we found strong associations between gut microbial amino acid metabolism and specific microbial species in relation to clinical features of obesity.

Keyphrases

weight loss
metabolic syndrome
microbial community
insulin resistance
bariatric surgery
type diabetes
amino acid
obese patients
high fat diet induced
weight gain
adipose tissue
body mass index
skeletal muscle
bone mineral density
climate change
body composition
postmenopausal women