Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM.
Matteo BassettiDaniele R GiacobbeChristina Agvald-OhmanMurat AkovaAna Alastruey-IzquierdoSevtap Arikan-AkdagliElie AzoulayStijn BlotOliver A CornelyManuel Cuenca-EstrellaDylan W de LangeFrancesco G De RosaJan J De WaeleGeorge DimopoulosJose Garnacho-MonteroMartin HoeniglSouha S KanjPhilipp KoehlerBart J KullbergFrédéric LamothCornelia Lass-FlörlJohan MaertensIgnacio Martin-LoechesPatricia MuñozGaryphallia PoulakouJordi RelloMaurizio SanguinettiFabio S TacconeJean-François TimsitAntoni TorresJose A VazquezJoost WautersErika AspergesAndrea CortegianiCecilia GrecchiIlias KaraiskosClément Le BihanToine MercierKlaus L MortensenMaddalena PeghinChiara RebuffiSofia TejadaAntonio VenaValentina ZuccaroLuigia ScudellerThierry Calandranull nullPublished in: Intensive care medicine (2024)
Standardized research definitions were developed for proven invasive candidiasis, probable deep-seated candidiasis, proven invasive aspergillosis, probable invasive pulmonary aspergillosis, and probable tracheobronchial aspergillosis. The limited evidence on the performance of existing definitions and laboratory tests for the diagnosis of IFD other than candidiasis and aspergillosis precluded the development of dedicated definitions, at least pending further data. The standardized definitions provided in the present document are aimed to speed-up the design, and increase the feasibility, of future comparative research studies.