Heparanase Overexpresses in Keratoconic Cornea and Tears Depending on the Pathologic Grade.
Beatriz GarcíaOlivia García-SuárezJesús Merayo-LlovesGuilherme FerraraIgnacio AlcaldeJavier GonzálezCarlos LisaJose F AlfonsoFernando VazquezLuis M QuirósPublished in: Disease markers (2017)
Heparanase overexpresses in keratoconic corneas, possibly reinforcing the inflammatory condition of the pathology. The presence of heparanase activity in tears allows us to propose its use as a biomarker for the diagnosis of the disorder.