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Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.

Manjunath Amit P PaiSirima SitarunoMohamed Abdelnabi
Published in: Pharmacotherapy (2022)
Race is not a relevant covariate of aminoglycoside CL. The 2021 CKD-EPI eGFR equation without race and BSA indexation is a better method for gentamicin and tobramycin CL estimation. Confirmation of these results for other drugs can support the harmonization of dosing by kidney function.
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