DXA-Derived Visceral Adipose Tissue (VAT) in Elderly: Percentiles of Reference for Gender and Association with Metabolic Outcomes.
Daniele SpadacciniTariq A AlalwanGabriella PeroniGiuseppe D'AntonaGiancarlo IannelloAlessandro FaragliVittoria InfantinoAntonella RivaGiovanna PetrangoliniMassimo NegroClara GasparriMariangela RondanelliPublished in: Life (Basel, Switzerland) (2020)
This study aimed to establish the Dual-Energy X-ray Absorptiometry (DXA)-derived Visceral adipose tissue (VAT) reference values for gender and assess the metabolic outcomes associated to the VAT in a cohort of elderly patients. The sample included 795 elderly patients (226/569: men/women) aged 65-100 years (mean age 80.9 ± 7.5ys). Body composition measures and VAT were assessed by DXA and Core-Scan software. Biochemical analysis and a multidimensional comprehensive geriatric assessment were performed. VAT percentiles at the level of 5, 25, 50, 75, 95 were found in males at the following levels: 246, 832, 1251, 1769, 3048 cm3 and for females at 99, 476, 775, 1178, 2277 cm3. Moreover, this study showed that DXA-VAT was associated to a worsening of lipid, glycemic, hematocrit and kidney profile. Further studies will be needed in order to implement these findings in order to define the (DXA)-derived VAT levels associated to the frailty related risk factors in elderly.
Keyphrases
- dual energy
- body composition
- computed tomography
- bone mineral density
- adipose tissue
- image quality
- insulin resistance
- resistance training
- risk factors
- middle aged
- contrast enhanced
- community dwelling
- postmenopausal women
- polycystic ovary syndrome
- magnetic resonance
- skeletal muscle
- data analysis
- high intensity
- psychometric properties