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Associations between systemic inflammation and somatic depressive symptoms: Findings from the Moli-sani study.

Alessandro GialluisiAugusto Di CastelnuovoFrancesca BraconeAmalia De CurtisChiara CerlettiMaria Benedetta DonatiGiovanni de GaetanoLicia Iacoviello
Published in: Depression and anxiety (2020)
This study provides a robust replication of the association previously reported between CRP and altered appetite in a large US population cohort, and supports a link between systemic inflammation, altered appetite, and tiredness. Moreover, it extends this evidence to inflammatory markers other than CRP and suggests new targets for the treatment of atypical depression.
Keyphrases
  • depressive symptoms
  • body weight
  • dna methylation
  • copy number
  • combination therapy
  • smoking cessation