Topical tranexamic acid in cemented primary total knee arthroplasty without tourniquet: a prospective randomized study.
Manuel Morales SantiasJesus Mas MartinezJavier Sanz-ReigEnrique Martínez GimenezCarmen Verdu RománDavid Bustamante Suarez de PugaPublished in: European journal of orthopaedic surgery & traumatology : orthopedie traumatologie (2020)
A single dose of 2-g TXA in 50 mL topical administration significantly reduces blood loss and improves postoperative blood chemistries in patients undergoing unilateral primary cemented TKA without tourniquet and drain compared to a control group, without increasing the risk of thromboembolic complications.