Association of leptin with disease severity and inflammation indicators in Chinese obese children with allergic rhinitis.
Wen Long LiuQingxiang ZengLifeng ZhouRenzhong LuoHaipeng DongPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2018)
Our study shows that obesity exacerbates inflammation and contributes to disease severity in AR. Our study provides evidence that leptin was involved in enhanced TH inflammation as well as the accumulation and activation of inflammatory cells in obese children with AR.