Characterization of thrombin/factor Xa inhibitors in Rhizoma Chuanxiong through UPLC-MS-based multivariate statistical analysis.

Yi-Yao YangZhao-Yu WuFang-Bo XiaHao ZhangXu WangJian-Li GaoFeng-Qing YangJian-Bo Wan

Published in: Chinese medicine (2020)

THR/FXa inhibitory components in different extracts of Chuanxiong were successfully characterized by the method of enzyme inhibition activity assays with ultra performance liquid chromatography-quadrupole time of flight mass spectrometry-based multivariate statistical analysis.

Keyphrases

liquid chromatography
mass spectrometry
simultaneous determination
tandem mass spectrometry
high resolution mass spectrometry
high resolution
data analysis
high performance liquid chromatography
gas chromatography
high throughput
solid phase extraction
ms ms