Population Pharmacokinetics of Sacituzumab Govitecan in Patients with Metastatic Triple-Negative Breast Cancer and Other Solid Tumors.
Abhishek G SatheIndrajeet SinghPratap SinghPaul M DiderichsenXiaohui WangPeter ChangAtiya TaquiSee PhanSandhya GirishAhmed A OthmanPublished in: Clinical pharmacokinetics (2024)
These analyses support the approved SG dosing regimen of 10 mg/kg as intravenous infusion on days 1 and 8 of 21-day cycles and did not identify a need for dose adjustment based on evaluated covariates or disease characteristics.