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Screening and characterisation of potential antioxidant, hypoglycemic and hypolipidemic components revealed in Portulaca oleracea via multi-target affinity ultrafiltration LC-MS and molecular docking.

Hui ZhangGuilin ChenJinpeng YangChunlei YangMing-Quan Guo
Published in: Phytochemical analysis : PCA (2021)
The present study revealed that P. oleracea can be used as a functional food with excellent antioxidant, hypoglycemic and hypolipidemic effects. Meanwhile, the integrated strategy based on multi-target UF-LC-MS and molecular docking also provided a powerful tool and a multidimensional perspective for further exploration of active ingredients in P. oleracea responsible for the antioxidant, hypoglycemic and hypolipidemic activities.
Keyphrases
  • molecular docking
  • oxidative stress
  • molecular dynamics simulations
  • anti inflammatory
  • single cell
  • human health