Risks of late mortality and morbidity among survivors of childhood acute leukemia with Down syndrome: A population-based cohort study.
Sumit GuptaRinku SutradharPriscila PequenoJohann K HitzlerNing LiuPaul C NathanPublished in: Cancer (2021)
DS survivors were at substantially higher risk of late mortality than non-DS survivors or DS controls. This excess risk was not attributable to cardiac- or subsequent malignant neoplasm-related late effects, historically main causes of premature death among non-DS survivors. Chronic morbidities associated with DS were not increased compared to DS controls. DS-specific surveillance guidelines may be warranted.