VMAP: Vaginal Microbiome Atlas During Pregnancy.
Antonio Parraga LeoTomiko T OskotskyBoris OskotskyCamilla WibrandAlennie RoldanAlice TangConnie W Y HaRonald J WongSamuel S MinotGaia AndreolettiIdit KostiKevin R TheisSherrianne NgYun S LeePhil R BennettDavid A MacIntyreSusan V LynchRoberto RomeroAdi L TarcaDavid K StevensonNima AghaeepourJonathan GolobMarina SirotaPublished in: medRxiv : the preprint server for health sciences (2023)
The vaginal microbiome has been shown to be associated with pregnancy outcomes including preterm birth (PTB) risk. Here we present VMAP: Vaginal Microbiome Atlas during Pregnancy (http://vmapapp.org), an application to visualize features of 3,909 vaginal microbiome samples of 1,416 pregnant individuals from 11 studies, aggregated from raw public and newly generated sequences via an open-source tool, MaLiAmPi. Our visualization tool (http://vmapapp.org) includes microbial features such as various measures of diversity, VALENCIA community state types (CST), and composition (via phylotypes and taxonomy). This work serves as a resource for the research community to further analyze and visualize vaginal microbiome data in order to better understand both healthy term pregnancies and those associated with adverse outcomes.