Gene-Environment Interactions in Multiple Sclerosis: A UK Biobank Study.

Benjamin Meir JacobsAlastair J NoyceJonathan BestwickDaniel BeleteGavin GiovannoniRuth Dobson

Published in: Neurology(R) neuroimmunology & neuroinflammation (2021)

This study provides novel evidence for an interaction between childhood obesity and a high burden of autosomal genetic risk. These findings may have significant implications for our understanding of MS biology and inform targeted prevention strategies.

Keyphrases

multiple sclerosis
genome wide
copy number
dna methylation
drug delivery
transcription factor