Protein Tyrosine Phosphatase SHP2 in Macrophages Acts as an Antiatherosclerotic Regulator in Mice.

Chenxia WuPeiyao ZhengLan MaChen XuLuoxia HuZhiyi YangFan FeiZhuxia ShenXue ZhangZiheng WuHongqiang ChengWei MaoYuehai Ke

Published in: Arteriosclerosis, thrombosis, and vascular biology (2023)

Overall, SHP2 in macrophages was found to act as an antiatherosclerotic regulator by stabilizing PPARγ in APOE/low-density lipoprotein receptor null mice.

Keyphrases

low density lipoprotein
high fat diet induced
transcription factor
insulin resistance
cognitive decline
binding protein
type diabetes
wild type
adipose tissue
amino acid
skeletal muscle
protein kinase
mild cognitive impairment