TNF blockade enhances the efficacy of myxoma virus-based oncolytic virotherapy.
Miriam Valenzuela-CardenasCody GowanParker DryjaMee Y BarteeEric BarteePublished in: Journal for immunotherapy of cancer (2022)
These data suggest that some aspects of OV-induced inflammation might represent a double-edged sword during therapy and that specific blockade of TNF might enhance the efficacy of these treatments.