Scutellarin improves the radiosensitivity of non-small cell lung cancer cells to iodine-125 seeds via downregulating the AKT/mTOR pathway.

Guang-Hui HeDian-Jin XingDie JinYue LuLei GuoYu-Liang Li Dong Li

Published in: Thoracic cancer (2021)

The results of our study suggested that SCU promotes the anticancer effects induced by 125 I in NSCLC cells by downregulating the AKT/mTOR pathway and lays a foundation for future application of this combined treatment.

Keyphrases

cell proliferation
signaling pathway
induced apoptosis
small cell lung cancer
cell cycle arrest
single cell
cell therapy
current status
pi k akt
magnetic resonance imaging
endoplasmic reticulum stress
computed tomography
stem cells
magnetic resonance
oxidative stress
cell death
tyrosine kinase