Novel evidence for m6A methylation regulators as prognostic biomarkers and FTO as a potential therapeutic target in gastric cancer.

Tadanobu ShimuraRaju KandimallaYoshinaga OkugawaMasaki OhiYuji ToiyamaChuan HeAjay Goel

Published in: British journal of cancer (2021)

We demonstrate that m6A regulators may serve as promising prognostic biomarkers in GC. Our functional studies reveal that FTO is an important oncogene and may be a promising therapeutic target associated with EMT-alterations in gastric cancer.

Keyphrases

genome wide
transcription factor
epithelial mesenchymal transition
dna methylation
risk assessment
high resolution
gas chromatography
liquid chromatography
simultaneous determination