Granulomas in Diagnostic Biopsies Associated With High Risk of Crohn's Complications-But May Be Preventable.

Lindsey S LawrenceAmer HeiderAndrew A M SingerHaley C NeefJeremy Adler

Published in: Inflammatory bowel diseases (2021)

Granulomas are associated with increased risk of perianal fistula but not stricture. Steroid sparing therapies seem to reduce the risk of both perianal fistula and stricture. For those with granulomas, anti-TNF-α therapy greatly reduced the risk of perianal fistula development, whereas immunomodulators did not.

Keyphrases

hidradenitis suppurativa
rheumatoid arthritis
endoscopic submucosal dissection
risk factors
emergency department
robot assisted
mesenchymal stem cells
bone marrow
ultrasound guided
chemotherapy induced