Albuminuria: An Underappreciated Risk Factor for Cardiovascular Disease.
Joshua I BarzilayYoussef M K FaragJeffrey DurthalerPublished in: Journal of the American Heart Association (2024)
Albuminuria, an established biomarker of the progression of chronic kidney disease, is also recognized as a biomarker for the risk of cardiovascular disease. Elevated urinary albumin excretion indicates kidney damage and systemic vascular disease, including myocardial capillary disease and arterial stiffness. Albuminuria is associated with an increased risk of coronary artery disease, stroke, heart failure, arrhythmias, and microvascular disease. There are now several therapeutic agents that can lead to albuminuria lowering and a reduction in cardiovascular risk. However, screening for albuminuria is still low. Considering the importance of multidisciplinary management of patients with cardiovascular disease, it is crucial that health care professionals managing such patients are aware of the benefits of albuminuria surveillance and management.
Keyphrases
- cardiovascular disease
- chronic kidney disease
- end stage renal disease
- heart failure
- coronary artery disease
- healthcare
- type diabetes
- public health
- left ventricular
- oxidative stress
- cardiovascular events
- newly diagnosed
- blood pressure
- metabolic syndrome
- cardiovascular risk factors
- prognostic factors
- percutaneous coronary intervention
- congenital heart disease
- coronary artery bypass grafting
- aortic valve
- social media
- blood brain barrier
- acute coronary syndrome