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Radiotherapy-Activated Hafnium Oxide Nanoparticles Produce Abscopal Effect in a Mouse Colorectal Cancer Model.

Ping ZhangAudrey DarmonJulie MarillNaeemunnisa Mohamed AnesarySébastien Paris
Published in: International journal of nanomedicine (2020)
These data show that radiotherapy-activated NBTXR3 could increase local and distant tumor control through immune system priming. Our results may have important implications for immunotherapeutic agent combination with radiotherapy.
Keyphrases
  • early stage
  • locally advanced
  • radiation induced
  • oxide nanoparticles
  • radiation therapy
  • lymph node
  • rectal cancer
  • squamous cell carcinoma
  • electronic health record
  • big data
  • deep learning
  • data analysis