Kidney function and the comparative effectiveness and safety of direct oral anticoagulants versus warfarin in adults with atrial fibrillation: a multicenter observational study.
Min JunAnish ScariaJason AndradeSunil V BadvePeter BirksSarah E BotaAnna CampainOgnjenka DjurdjevAmit X GargJeffrey HaZiv HarelBrenda HemmelgarnCarinna HockhamMatthew T JamesMeg J JardineAdeera LevinEric McArthurPietro RavaniSelena ShaoManish M SoodZhi TanNavdeep TangriReid H WhitlockMartin GallagherPublished in: European heart journal. Quality of care & clinical outcomes (2022)
DOAC use, compared with warfarin use, was associated with lower or similar risk of all-cause death, ischemic stroke and transient ischemic attack and also a lower or similar risk of major bleeding across all levels of kidney function.
Keyphrases
- direct oral anticoagulants
- atrial fibrillation
- oral anticoagulants
- catheter ablation
- left atrial
- venous thromboembolism
- left atrial appendage
- cerebral ischemia
- heart failure
- percutaneous coronary intervention
- ischemia reperfusion injury
- double blind
- coronary artery disease
- subarachnoid hemorrhage
- blood brain barrier