Diastolic dysfunction in severe aortic stenosis: Old but still gold.
Cinzia PerrinoGiovanni EspositoPublished in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2020)
A simple, widely applicable and reproducible risk predictor may improve patient care, risk stratification, and clinical decision making for symptomatic severe aortic stenosis (sAS) patients undergoing transcatheter aortic valve implantation (TAVI). Baseline severe left ventricular diastolic dysfunction identified by E/A ratio in sAS patients undergoing TAVI is associated with increased post-procedural all-cause mortality or heart failure hospitalization but is not an independent predictor of outcome. Large studies employing multimodality imaging of cardiac function/structure and accounting for sex and comorbidities will be necessary to validate DD parameters (or their combination) in sAS patients undergoing TAVI.
Keyphrases
- aortic stenosis
- left ventricular
- transcatheter aortic valve implantation
- patients undergoing
- ejection fraction
- aortic valve replacement
- heart failure
- transcatheter aortic valve replacement
- aortic valve
- cardiac resynchronization therapy
- hypertrophic cardiomyopathy
- acute myocardial infarction
- left atrial
- mitral valve
- early onset
- decision making
- oxidative stress
- coronary artery disease
- high resolution
- blood pressure
- percutaneous coronary intervention
- atrial fibrillation
- silver nanoparticles