Novel genetic locus at MHC region for esophageal squamous cell carcinoma in Chinese populations.

Peng ZhangXin-Min LiXue-Ke ZhaoXin SongLing YuanFang-Fang ShenZong-Min FanLi Dong Wang

Published in: PloS one (2017)

The rs911178 (SCAND3 gene) in MHC region is significantly associated with high risk of ESCC. This study not only reveal the potential role of MHC region for the pathogenesis of ESCC, but also provides important clues for the establishment of tools and methods for screening high risk population of ESCC.

Keyphrases

genome wide
copy number
gene expression